Effect of drugs on carbohydrate metabolism

Effect of drugs on carbohydrate metabolism.

Many drugs affect carbohydrate metabolism in man. For some this is the action that is sought and the reason for their inclusion in the pharmacopoeia; for others it is an epiphenomenon or undesirable side-effect which may or may not be predictable. Broadly speaking, drugs that affect carbohydrate metabolism can be divided (Table I) into those that tend: (a) to raise the fasting blood glucose con...

Effects of Benzothiadiazine Drugs on Carbohydrate Metabolism.

The administration of chlorothiazide both to man and to rats results in hyperglycemia following a glucose load. Its administration to rats causes a decreased rate of glucose utilization by their adipose tissue in vitro. Chlorothiazide added directly to the incubating medium also decreases the rate of glucose utilization of rat adipose tissue. These effects of chlorothiazide are most likely due ...

The effect of maternal hypothyroidism during pregnancy on carbohydrate metabolism in adulthood in rats

Introduction: Many of the diseases of adulthood are originated from the intrauterine conditions during fetal life. Because of the importance of thyroid hormones in growth and development of the fetus, the effects of maternal hypothyroidism on carbohydrate metabolism in adulthood was investigated. Methods: Pregnant rats were divided into the fetal hypothyroidism (FH) and the control (C) group...

The effect of chronic psychological stress on carbohydrate metabolism in rat

Several studies have shown that stress has major effects on metabolism. There is also some evidence indicating that stress may induce diabetes mellitus. The present study has investigated the role of chronic psychological stress on carbohydrate metabolism in male Wistar rats (250 ± 50 g). Animals were divided into control and test groups (n = 8/group). Blood samples were obtained by tail snippi...

Effect of insulin on carbohydrate metabolism.